| County/City | Population 1980 | Population 1990 | Percent Change 1980-1990 | Population 2000 | Percent Change 1990-2000 |
|---|---|---|---|---|---|
| Cameron County | 209,727 | 260,120 | 24.0 | 335,227 | 28.9 |
| Bayview Town | 291 | 231 | -20.6 | 323 | 39.8 |
| Brownsville City | 84,997 | 98,962 | 16.4 | 139,722 | 41.2 |
| Cameron Park CDP | 5,721 | 3,802 | 33.5 | 5,961 | 56.8 |
| Combes Town | 1,488 | 2,042 | 37.2 | 2,553 | 25.0 |
| Encantada - Ranchito CDP | - | 1,143 | - | 2,100 | 83.7 |
| Harlingen City | 43,543 | 48,746 | 11.9 | 57,564 | 18.1 |
| Indian Lake Town | - | 390 | - | 541 | 38.7 |
| La Feria City | 3,495 | 4,360 | 24.7 | 6,115 | 40.3 |
| Laguna Heights CDP | - | 1,671 | - | 1,990 | 19.1 |
| Laguna Vista | 632 | 1,166 | 84.5 | 1,658 | 42.2 |
| Los Fresnos | 2,173 | 2,473 | 13.8 | 4,512 | 82.5 |
| Palm Valley Town | - | 1,199 | - | 1,298 | 8.3 |
| Port Isabel City | 3,769 | 4,467 | 18.5 | 4,865 | 8.9 |
| Primera Town | 1,380 | 2,030 | 47.1 | 2.723 | 34.1 |
| Rancho Viejo | - | 885 | - | 1,754 | 98.2 |
| Rangerville | - | 280 | - | 203 | -27.5 |
| Rio Hondo City | 1,673 | 1,793 | 7.2 | 1,942 | 8.3 |
| San Benito City | 17,988 | 20,125 | 11.9 | 23,444 | 16.5 |
| Santa Rosa Town | 1,889 | 2,223 | 17.7 | 2,833 | 27.4 |
| South Padre Island | 791 | 1,677 | 112.0 | 2,422 | 44.4 |